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Diss Factsheets

Physical & Chemical properties

Particle size distribution (Granulometry)

Administrative data

Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2019
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2019
Report date:
2019

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
ISO 13320 (Particle size analysis - Laser diffraction methods)
Version / remarks:
2009
Deviations:
no
Qualifier:
according to guideline
Guideline:
other: • CIPAC MT 187: Particle Size Analysis by Laser Diffraction, Handbook K
Version / remarks:
2007
Deviations:
no
GLP compliance:
yes
Type of method:
Laser scattering/diffraction
Type of particle tested:
primary particle
Type of distribution:
volumetric distribution

Test material

Constituent 1
Chemical structure
Reference substance name:
(2,4-dioxo-1,3-benzoxazin-7-yl) ethyl carbonate
EC Number:
605-404-6
Cas Number:
16535-55-0
Molecular formula:
C11 H9 N O6
IUPAC Name:
(2,4-dioxo-1,3-benzoxazin-7-yl) ethyl carbonate
Test material form:
solid: particulate/powder
Details on test material:
Off-white crystalline powder

Results and discussion

Mass median aerodynamic diameter:
183 µm
Geometric standard deviation:
>= 1.591 - <= 1.636
Particle sizeopen allclose all
Percentile:
D10
Mean:
78.6 µm
St. dev.:
1.46
Percentile:
D50
Mean:
149 µm
St. dev.:
3.44
Percentile:
D90
Mean:
264 µm
St. dev.:
11.8
Percentile:
other: mode
Mean:
155 µm
St. dev.:
2.48
Percentile:
other: Volume weighted mean
Mean:
161 µm
St. dev.:
5.26

Applicant's summary and conclusion

Conclusions:
The particle size distribution of the test item was determined by means of Laser Diffraction Analysis using the medium volume (wet) module (MVM). PEG 300 was used as the dispersant in the analysis.
The D50 of the test item was determined to be 149 µm, the D10 was 78.6 µm and the D90 was 264 µm. The MMAD of the test item was calculated to be 183 µm.