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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2019
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Report date:
2019

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
1995
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Version / remarks:
2016
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7840 (Water Solubility)
Version / remarks:
1998
Deviations:
no
GLP compliance:
yes
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
(2,4-dioxo-1,3-benzoxazin-7-yl) ethyl carbonate
EC Number:
605-404-6
Cas Number:
16535-55-0
Molecular formula:
C11 H9 N O6
IUPAC Name:
(2,4-dioxo-1,3-benzoxazin-7-yl) ethyl carbonate
Test material form:
solid: particulate/powder
Details on test material:
Off-white crystalline powder

Results and discussion

Water solubility
Water solubility:
0.098 g/L
Conc. based on:
test mat.
Loading of aqueous phase:
0.11 g/L
Temp.:
20 °C
pH:
>= 6.5 - <= 6.6
Details on results:
The maximum difference of the concentrations determined in the 24, 48 and 72 hour test samples was ≤ 15%. Based on this, the water solubility of the test item is given as the mean value of the analyzed concentrations.
Small responses at the retention time of the test item were detected in the chromatograms of the pretreated sample from the blank water mixture. The maximum contribution to the samples was 0.0045%. It was considered that it has no significant effect on the results of the test samples

Applicant's summary and conclusion

Conclusions:
The flask method was applied for the determination of the water solubility of CH02672.
The water solubility of the test item at 20°C was 0.0979 g/L.
The pH of the aqueous samples was 6.5 and 6.6.