Registration Dossier
Registration Dossier
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EC number: 220-489-6 | CAS number: 2783-17-7
Endpoint summary
Administrative data
Description of key information
in literature, some data on acute toxicity is present.
Acute Toxicity Data Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990-
states an LDlo (oral, rat) of 670 mg/kg
Inhalation Toxicology (Published by Taylor & Francis Health, 11 New Fetter Lane, London EC4P 4EE) V.1- 1989-
states an LD50 (inhalation, rat, 4h) 680 mg/m3
However, as the substance is classified as skin corrosive, cat. 1, no study is reported.
Key value for chemical safety assessment
Acute toxicity: via oral route
Link to relevant study records
- Endpoint:
- acute toxicity: oral
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the substance is classified as corrosive to the skin
Reference
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed
- Dose descriptor:
- discriminating dose
- Value:
- 670 mg/kg bw
- Quality of whole database:
- some studies present in literature, however no LD50 stated. As Endpoint conclusion, an LDlo value is taken.
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed
- Dose descriptor:
- LC50
- Value:
- 680 mg/m³ air
- Quality of whole database:
- studies present in literature
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for classification or non-classification
Available information is sufficient for classification as:
oral toxicity, cat. 4
toxic after inhalation, cat. 3
in addition, based on the corrosivity of the substance, it shall be stated "corrosive on respiratory tract"
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