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Physical & Chemical properties

Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
12 Aug 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
EU Method A.8 (Partition Coefficient - Shake Flask Method)
Qualifier:
according to
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Deviations:
no
GLP compliance:
no
Type of method:
flask method
Partition coefficient type:
octanol-water
Key result
Type:
log Pow
Partition coefficient:
> 6
Temp.:
25 °C
Remarks on result:
other: no pH value available
Conclusions:
The test item was found to be immiscible in both water and octanol therefore formal testing was not possible. Estimation by software was performed.

Software Estimation
The prediction software uses SMILES input to calculate the Partition Coefficient. In accordance with the test guidance the partition coefficient was estimated using prediction software (KOWWIN v1.68)

Description of key information

The test item was found to be immiscible in both water and octanol therefore formal testing was not possible. Estimation by software was performed. 

The prediction software uses SMILES input to calculate the Partition Coefficient. In accordance with the test guidance the partition coefficient was estimated using prediction software (KOWWIN v1.68)

Key value for chemical safety assessment

Log Kow (Log Pow):
6
at the temperature of:
25 °C

Additional information