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EC number: 500-607-5 | CAS number: 161278-17-7
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- >= 0.646 - <= 2.42
- Temp.:
- 25 °C
- pH:
- ca. 7.9
- Conclusions:
- The partition coefficient of the test item has been determined to be in the range 2.58 to 7.68 x 104, log10 Pow of 0.41 to 4.89. For approximately 88% of the test item by peak area normalisation the partition coefficient was in the range 2.58 to 144, log10 Pow of 0.41 to 2.16.
- Executive summary:
In the range 2.58 to 7.68 x 104, log10 Pow of 0.41 to 4.89, using the HPLC method, designed to be compatible with Method A.8 Partition Coefficient of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 117 of the OECD Guidelines for Testing of Chemicals, 13 April 2004.
For approximately 88% of the test item by peak area normalisation the partition coefficient was in the range 2.58 to 144, log10 Pow of 0.41 to 2.16.
Reference
Description of key information
The partition coefficient of the test item has been determined in the range 4.42 to 262, log10 Pow 0.646 to 2.42.
Key value for chemical safety assessment
Additional information
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