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Physical & Chemical properties

Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1987
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
other: EU Method A.8
Deviations:
no
GLP compliance:
not specified
Type of method:
estimation method (solubility ratio)
Partition coefficient type:
octanol-water
Specific details on test material used for the study:
- GLP sample 706
Analytical method:
other: Spectrophotometric
Key result
Type:
log Pow
Partition coefficient:
< -3.8
Temp.:
25 °C
pH:
7
Remarks on result:
other: Mean of 5 tested values
Conclusions:
Under the study condtions, the partition coefficient  (Log Kow) of the substance was determined to be <-3.8 at 25˚C.
Executive summary:

A study was conducted to determine the partition coefficient fo the substance according to EU Method A.8. Test substance concentrations were measured spectrophotometrically by comparision with a calibration curve prepared in distilled water. Under the study condtions, the partition coefficient  (Log Kow) of the substance was determined to be <-3.8 at 25˚C (Macnab, 1987).

Description of key information

The partition coefficient (n-octanol/water) was determined according to EU Method A.8 (Macnab, 1987).

Key value for chemical safety assessment

Log Kow (Log Pow):
-3.8
at the temperature of:
25 °C

Additional information