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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From October 1997 to March 1998
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods with acceptable restrictions
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
other: successive addition of water to test substance and reverse procedure
Key result
Conc. based on:
test mat.
Loading of aqueous phase:
54.2 other: %
Temp.:
25 °C
Remarks on result:
other: fully miscible in each ratio
Details on results:
Results for both 1 and 2:
The resulting mixture was homogeneous for each ratio between test substance and water. In other words: At each ratio, it was not possible to distinguish between (saturated) aqueous solution and non-dissolved test substance. Consequently, the test substance is miscible with water in each ratio.
Conclusions:
Under the study conditions, the test substance was completely miscible with water in each ratio.
Executive summary:

A study was conducted to determine the solubility of the test substance in water according to EU Method A.6, preliminary test, in compliance with GLP. Measurements were conducted at 25°C. Under the study conditions, the test substance was completely miscible with water in each ratio (Gorsenick, 1997).

Description of key information

The solubility in water was determined according to EU Method A.6, preliminary test (Gorsenick, 1997).

Key value for chemical safety assessment

Water solubility:
1 000 g/L
at the temperature of:
25 °C

Additional information

The test substance is completely miscible with water in each ratio.