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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
30 May - 17 Jul 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
no
Type of method:
column elution method
Key result
Water solubility:
< 0.56 µg/L
Temp.:
20 °C
pH:
6.3

The concentrations of the test item in the different test solutions were calculated automatically using the equation of the calibration curve. The results are listed in the following table:

 

Flow rate

[mL/h]

Fraction No.

Volume of combined fractions

[mL]

Internal Standard

[µg/L]

Test Item

[µg/L]

6.25

1 (1-2)

20

102.58

< 0.56

2 (3-4)

20

102.58

< 0.56

3 (5-6)

20

102.58

< 0.56

4 (7-8)

20

102.58

< 0.56

5 (9-10)

20

102.58

< 0.56

6 (11-12)

20

102.58

< 0.56

7 (13-14)

20

102.58

< 0.56

8 (15-16)

20

102.58

< 0.56

3.25

1 (1-2)

20

102.58

< 0.56

2 (3-4)

20

102.58

< 0.56

3 (5-6)

20

102.58

< 0.56

4 (7-8)

20

102.58

< 0.56

5 (9-10)

20

102.58

< 0.56

6(11-12)

20

102.58

< 0.56

7(13-14)

20

102.58

< 0.56

8 (15-16)

20

102.58

< 0.56

 

The test item could not be detected in the collected fractions, hence the water solubility of the test item is considered to be below the detection limit of the analytical method (< 0.56 µg/L).

 

With reference to column 2 of Annex VII to REACH "If the substance appears 'insoluble' in water, a limit test up to the detection limit of the analytical method shall be performed", the water solubility of the test item is reported as < 0.56 µg/L.

 

The water solubility was determined at 20 °C.

The pH value of the collected aqueous fractions was 6.3.

Description of key information

Water solubility < 0.56 µg/L at 20 °C, pH 6.3 (OECD Guideline 105, column elution method)

Key value for chemical safety assessment

Additional information

The test item could not be detected in the collected fractions, hence the water solubility of the test item is considered to be below the detection limit of the analytical method (< 0.56 µg/L).