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Physical & Chemical properties

Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
Study period:
2018-01-05
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method
Reason / purpose:
reference to other study
Reason / purpose:
reference to other study
Qualifier:
no guideline followed
Principles of method if other than guideline:
As suggested in OECD TG 107, the partition coefficient is determined from the individual solubilities in water and n-octanol since earlier investigations showed that neither the shake-flask or HPLC methods were suitable for this substance.
GLP compliance:
not specified
Type of method:
estimation method (solubility ratio)
Partition coefficient type:
octanol-water
Type:
log Pow
Partition coefficient:
> 3.39
Temp.:
20 °C
pH:
2.17

The water solubility was determined to be 0.21 g/L

The solubility in n-octanol was determined to be >2.0 kg/L or rather unlimited

Conclusions:
Log Kow > 3.98
Executive summary:

The partition coefficient of the test item was calculated from the individual solubilities in n-octanol and water at 20 °C. The Log Kow >3.98.

Description of key information

Log Kow >3.98.

Key value for chemical safety assessment

Log Kow (Log Pow):
3.98
at the temperature of:
20 °C

Additional information

The partition coefficient of the test item was calculated from the individual solubilities in n-octanol and water at 20 °C. The Log Kow >3.98.