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Environmental fate & pathways

Biodegradation in water: screening tests

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Reference
Endpoint:
biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
GLP compliance:
yes
Oxygen conditions:
not specified
Inoculum or test system:
not specified
Details on inoculum:
Control solutions with inoculum and sodium benzoate, as standard material, were used for validation purposes.
Details on study design:
A study was performed to assess the ready biodegradability of the test material in an aerobic aqueous media. The method followed that described in OECD 301B guideline. The test material was exposed to activated sewage sludge micro-organisms at a concentration of 10 mg C/I with culture medium in sealed culture vessels in the dark at 21°C for 28 days. The degradation of the substance was assessed by the determination of carbon dioxide produced on sampling days 0, 1, 2, 3, 6, 8, 14, 20, 22, 24, 27, 28 and 29. Control solutions with inoculum and sodium benzoate, as standard material, were used for validation purposes.
Key result
Parameter:
% degradation (CO2 evolution)
Value:
ca. 74
Sampling time:
28 d
Details on results:
The degradation of the substance was assessed by the determination of carbon dioxide produced on sampling days 0, 1, 2, 3, 6, 8, 14, 20, 22, 24, 27, 28 and 29. Control solutions with inoculum and sodium benzoate, as standard material, were used for validation purposes. The substance attained 74% degradation after 28 days and met the 10-day window validation criterion.
Validity criteria fulfilled:
not specified
Interpretation of results:
readily biodegradable
Conclusions:
The substance can therefore be considered to be readily biodegradable under the strict terms and conditions of OECD 301B guideline

Description of key information

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable

Additional information