Registration Dossier
Registration Dossier
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EC number: 246-857-6 | CAS number: 25333-42-0
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7840 (Water Solubility)
- GLP compliance:
- yes
- Type of method:
- other: visual determination
Test material
- Reference substance name:
- (R)-quinuclidin-3-ol
- EC Number:
- 246-857-6
- EC Name:
- (R)-quinuclidin-3-ol
- Cas Number:
- 25333-42-0
- Molecular formula:
- C7H13NO
- IUPAC Name:
- quinuclidin-3-ol
- Test material form:
- solid: crystalline
Constituent 1
Results and discussion
Water solubility
- Water solubility:
- > 1 000 g/L
- Conc. based on:
- test mat.
- Incubation duration:
- 1 d
- Temp.:
- 20 °C
- pH:
- 12.7
- Details on results:
- After the stirring period, the test sample was clear and no undissolved test item was observed. It was concluded that the water solubility of R-Quinuclidinol at 20°C was > 1000 g/L. As
water solubility of the substance was determined from visual observation alone to be higher than 1:1 test item:water, no further testing was conducted to determine the actual water solubility value.
Applicant's summary and conclusion
- Conclusions:
- It was concluded that the water solubility of test substance at 20°C was > 1000 g/L.
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