Registration Dossier
Registration Dossier
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Benzenesulfonic acid, para-, monoalkylation products with C14-C18 branched olefins (C15 rich) derived from propene oligomerization, calcium salt, overbased including distillates (petroleum), hydrotreated, solvent-refined, solvent-dewaxed, or catalytic dewaxed, light or heavy paraffinic C15-C50
EC number: 701-205-4 | CAS number: -
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- October 13, 1997 - February 5, 1998
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 998
- Report date:
- 1998
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 402 (Acute Dermal Toxicity)
- Deviations:
- no
- GLP compliance:
- yes
- Test type:
- fixed dose procedure
- Limit test:
- yes
Test material
- Reference substance name:
- SP 6012
- IUPAC Name:
- SP 6012
- Details on test material:
- See attached study report for details
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Crj: CD(SD)
- Sex:
- male/female
- Details on test animals or test system and environmental conditions:
- See attached study report for details
Administration / exposure
- Type of coverage:
- semiocclusive
- Vehicle:
- unchanged (no vehicle)
- Details on dermal exposure:
- See attached study report for details
- Duration of exposure:
- 1, 2.5, 4 hours, and 14 day observations. See attached study report for details.
- Doses:
- 5,000 mg/kg bw (single dose)
- No. of animals per sex per dose:
- 5 males/ 5 females per single dose level
- Control animals:
- not required
- Details on study design:
- See attached study report for details
- Statistics:
- None required for study
Results and discussion
- Preliminary study:
- LD50 > 5000 mg/kg bw
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 5 000 mg/kg bw
- Mortality:
- No deaths occurred during the course of the study
- Clinical signs:
- other: Test material produced moderate to severe dermal irritation
- Gross pathology:
- See attached study report for details
- Other findings:
- See attached study report for details
Any other information on results incl. tables
See attached study report for details
Applicant's summary and conclusion
- Interpretation of results:
- study cannot be used for classification
- Remarks:
- Migrated information
- Conclusions:
- Estimated dermal LD50 for males and females is > 5,000 mg/kg bw
- Executive summary:
See attached study report for details
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