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Environmental fate & pathways

Biodegradation in water: screening tests

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Reference
Endpoint:
biodegradation in water: ready biodegradability
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Justification for type of information:
Please refer to the attached justification below and the overall justification for grouping of substances attached in IUCLID Section 13.
Reason / purpose:
read-across source
Key result
Parameter:
% degradation (inorg. C analysis)
Value:
0
Sampling time:
28 d
Validity criteria fulfilled:
yes
Interpretation of results:
under test conditions no biodegradation observed
Conclusions:
A biodegradation rate of 0% was determined in a reliable study conducted according to an appropriate test protocol, and in compliance with GLP.

Description of key information

Diethoxy(dimethyl)silane (CAS 78-62-6) is not readily biodegradable (0% after 28 d) based on read across from CAS 1066-40-6. 

Key value for chemical safety assessment

Biodegradation in water:
under test conditions no biodegradation observed

Additional information

There are no data on biodegradation for Diethoxy(dimethyl)silane (CAS 78-62-6). In accordance with Regulation (EC) No 1907/2006 Annex XI, 1.5 “Grouping of substances and read across” and in accordance with the Read across assessment framework (RAAF, ECHA 2017) a read across from the analogue substance trimethylsilanol (CAS 1066-40-6) has been applied to support the environmental hazard assessment of diethoxy(dimethyl)silane (CAS 78-62-6). Details on read across justifications can be found in the attached justification in the respective target entry and in the overall justification for grouping of substances attached in IUCLID Section 13. The available study (2008) investigating the biodegradation of the analogue substance trimethylsilanol (CAS 1066-40-6) was conducted according to OECD 310, under GLP conditions. The inoculum (non-adapted activated sludge from a sewage treatment plant) was exposed for 28 days to the test substance and biodegradation was calculated based on inorganic C-analysis. No biodegradation of the substance was recorded after 28 d (0.0%). Thus, the substance is not readily biodegradable according to the OECD criteria. Based on the results of the analogue substance, Diethoxy(dimethyl)silane (CAS 78-62-6) is not assumed to be readily biodegradable.