Registration Dossier

Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
1979
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: only orientating information about the inhalation hazard. No information on dose and particle size

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1979
Report Date:
1979

Materials and methods

Principles of method if other than guideline:
according to H.F. Smyth et al.: Am. Ind. Hyg. Ass. J. 23, 95 - 107 (1962)
GLP compliance:
no
Test type:
other: inhalation hazard test

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid
Details on test material:
Name of the test substance used in the study report: Scheckfarbstoff AS
The purity is stated as 100% of the drawn chemical structure in the order sheet. (Chemical structure is identical to the main component of the UVCB, CAS 6359-10-9)
The substance is stated to be a sales product.
The water solubility is indicated to be 20g/L. No information on pH is provided.
Specific details on test material used for the study:
Name of the test substance used in the study report: Scheckfarbstoff AS
Content: 100%

Test animals

Species:
rat
Sex:
male/female

Administration / exposure

Route of administration:
inhalation: dust
Details on inhalation exposure:
Air is blown through a layer of dusty material and this generates the test atmosphere.
Duration of exposure:
7 h
No. of animals per sex per dose:
12

Results and discussion

Mortality:
None
Clinical signs:
other: No abnormalities
Gross pathology:
Organs: no abnormalities detected

Applicant's summary and conclusion