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EC number: 257-581-0 | CAS number: 51988-14-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Particle size distribution (Granulometry)
Administrative data
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2017-01-12 - 2017-01-13 (experimental phase)
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- ISO 13320 (Particle size analysis - Laser diffraction methods)
- Version / remarks:
- 2009
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: CIPAC MT 187
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- by the Department of Health of the Government of the United Kingdom
- Type of method:
- Laser scattering/diffraction
- Type of particle tested:
- primary particle
- Type of distribution:
- volumetric distribution
Test material
- Reference substance name:
- (S)-(4,5-dihydro-5-thioxo-1,3,4-thiadiazol-2-yl) benzenecarbothioate
- EC Number:
- 257-581-0
- EC Name:
- (S)-(4,5-dihydro-5-thioxo-1,3,4-thiadiazol-2-yl) benzenecarbothioate
- Cas Number:
- 51988-14-8
- Molecular formula:
- C9H6N2OS3
- IUPAC Name:
- phenyl[(5-sulfanylidene-4,5-dihydro-1,3,4-thiadiazol-2-yl)sulfanyl]methanone
- Test material form:
- solid: particulate/powder
- Details on test material:
- - Density: 1.033 g/cm³
Constituent 1
- Specific details on test material used for the study:
- STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: At room temperature
Results and discussion
- Mass median aerodynamic diameter:
- 18.017 µm
- Geometric standard deviation:
- 0.14
Particle sizeopen allclose all
- Key result
- Percentile:
- D10
- Mean:
- 6.728 µm
- St. dev.:
- 0.035
- Key result
- Percentile:
- D50
- Mean:
- 17.727 µm
- St. dev.:
- 0.137
- Key result
- Percentile:
- D90
- Mean:
- 43.34 µm
- St. dev.:
- 0.67
Particle size distribution at different passagesopen allclose all
- No.:
- #1
- Size:
- < 15 µm
- Distribution:
- ca. 39.82 %
- No.:
- #2
- Size:
- < 50 µm
- Distribution:
- ca. 91.9 %
- No.:
- #3
- Size:
- < 100 µm
- Distribution:
- ca. 93.4 %
Applicant's summary and conclusion
- Conclusions:
- Particle size distribution was determined by a scientifically reasonably study according to ISO 13320:2009 and CIPAC MT 187 under GLP, so there is no reason to conclude that the results are not reliable. Particle size distribution of (S)-(4,5-dihydro-5-thioxo-1,3,4-thiadiazol-2-yl)benzenecarbothioate revealed a MMAD of 18.017 µm.
- Executive summary:
The results of the laser diffraction test conducted in accordance with ISO 13320:2009 and CIPAC MT 187 to determine the particle size of (S)-(4,5-dihydro-5-thioxo-1,3,4-thiadiazol-2-yl) benzenecarbothioate are summarised below. The analysis was conducted using the small volume (wet) module (SVM) with silicone oil as the dispersant.
Particle Size Analysis using small volume (wet) module (SVM)
Average (µm)
Volume weighted mean
27.628
Median
17.727
Mode
18.194
MMAD (mass median aerodynamic diameter)
18.017
d10 - 10 % of material is <
6.728
d50 - 50 % of material is <
17.727
d90 - 90 % of material is <
43.340
volume of sample < 10.00 µm
20.01 %
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