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Registration Dossier
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EC number: 220-474-4 | CAS number: 2778-42-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Density
Administrative data
Link to relevant study record(s)
- Endpoint:
- density
- Remarks:
- density
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1995
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
- Reason / purpose for cross-reference:
- reference to other study
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 109 (Density of Liquids and Solids)
- Deviations:
- no
- GLP compliance:
- not specified
- Type of method:
- pycnometer method
- Key result
- Type:
- density
- Density:
- 1.07 g/cm³
- Temp.:
- 25 °C
- Conclusions:
- Under the test conditions, the density of the test material was 1.06749 g/cm3 at 25 °C.
- Executive summary:
A study was performed to determine the density of the test material using a pycnometer at 25 °C. The study was conducted with a method equivalent or similar to OECD Guideline 109.
Under the test conditions, the density of the test material was 1.06749 g/cm3 at 25 °C.
- Endpoint:
- density
- Remarks:
- density
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From Jan. 28, 2010 to Feb. 02, 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 109 (Density of Liquids and Solids)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- oscillating densitimeter
- Key result
- Type:
- density
- Density:
- 1.074 other: g/mL
- Temp.:
- 20 °C
- Remarks on result:
- other: -
- Key result
- Type:
- density
- Density:
- 1.07 other: g/mL
- Temp.:
- 25 °C
- Remarks on result:
- other: -
- Conclusions:
- Under the test conditions, the density of the test material was determined to be 1.0742 and 1.0698 g/mL at 20 and 25 °C respectively.
- Executive summary:
A study was performed to determine the density of the test material using an Anton Paar DMA 4500 Digital Density Meter. The study was conducted according to OECD Guideline 109.
Duplicate measurements were made at 20 and 25 °C. NIST traceable toluene was used as a standard for instrument calibration.
Under the test conditions, the density of the test material was determined to be 1.0742 and 1.0698 g/mL at 20 and 25 °C respectively.
Referenceopen allclose all
Table 1. Density of TMXDI (meta) aliphatic isocyanate, S20176-46
Density (g/mL) |
Aliquot No. |
Temperature (°C) |
1.0742 |
1 |
20.0 |
1.0742 |
2 |
20.0 |
1.0698 |
1 |
25.0 |
1.0698 |
2 |
25.0 |
The repeatability was better than 0.0001 g/mL at both temperatures.
Description of key information
The density was determined according to OECD Guideline 109 (Pepe, 1995 and Rivera, 2010).
Key value for chemical safety assessment
- Relative density at 20C:
- 1.07
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

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