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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Genetic toxicity in vitro

Description of key information

DNNSA did not induce mutations in the Ames test and for BaDNNSA the chromosome aberration test and the mouse lymphoma test were negative. It is not expected that the barium cation will be of influence on the outcome of the testing. Therefore the tests on the salt will be used in a read-across approach.

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (negative)

Additional information

see read-across rationale in section 13

Justification for classification or non-classification

The test material, DNNSA and its Barium salt were negative in three in vitro genetic toxicity tests (Ames test, mouse lymphoma cell mutation assay and chromosome aberration test in human lymphocytes) and thus is not classified for genetic toxicity according to CLP (Regulation EC No 1272/2008) or DSD (Directive 67/548/EEC).