Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
other information
Study period:
30th December 1998 - 25th January 1999
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study without detailed documentation

Data source

Materials and methods

GLP compliance:
not specified
Test type:
standard acute method
Limit test:
no

Test animals

Species:
rat
Strain:
Sprague-Dawley
Sex:
male/female

Administration / exposure

Route of administration:
oral: gavage
Doses:
50, 150, 500 and 2,000 mg/kg
No. of animals per sex per dose:
5
Control animals:
not specified

Results and discussion

Mortality:
LD50 183 mg/kg body weight

Applicant's summary and conclusion