Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: other routes
Remarks:
Eye
Type of information:
experimental study
Adequacy of study:
other information
Study period:
15th January 1999
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Materials and methods

Test material

Specific details on test material used for the study:
To provide information on health hazards likely to arise from a single instillation of (S)-5-Methoxy-2-aminotetralin into the eyes of rabbits.

Test animals

Species:
rabbit
Strain:
New Zealand White
Sex:
male/female

Administration / exposure

Route of administration:
other: Added into the eye
Doses:
0.06 g
No. of animals per sex per dose:
2 males and 1 female

Results and discussion

Mortality:
All three were found dead within 1 hour of dosing.

Applicant's summary and conclusion