Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
October 2016
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
The determination was carried out using a procedure designed to be compatible with Method A.4 Vapour Pressure of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 104 of the OECD Guidelines for Testing of Chemicals, 23 March 2006.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2016
Report date:
2016

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: vapour pressure balance

Test material

Constituent 1
Chemical structure
Reference substance name:
604-144-0
EC Number:
604-144-0
Cas Number:
139525-77-2
Molecular formula:
C13H15NO.HCl
IUPAC Name:
604-144-0
Test material form:
solid: particulate/powder
Details on test material:
White powder
Specific details on test material used for the study:
Batch Number : 18113833

Results and discussion

Vapour pressure
Key result
Temp.:
ca. 25 °C
Vapour pressure:
ca. 5.4 Pa

Any other information on results incl. tables

Recorded temperatures, mass differences and the resulting calculated values of vapor pressure are shown in the joint document KS95WT.

A total of 6 runs were completed for the main sequence. The values of vapor pressure at 25 °C has been extrapolated from each graph. (see table 7 of the

KS95WT document).

Equilibrium with regard to vapor pressure was assessed to have been reached over these 6 runs. Thus all 6 runs have been used to calculate the definitive vapor pressure value for the test item.

Applicant's summary and conclusion

Conclusions:
The vapor pressure of the test item has been determined to be 5.4 x 10E-7 Pa at 25 ºC.
Executive summary:

The vapor pressure of Mephtamin-HCL has been determined to be 5.4 x 10E-7 Pa at 25 °C, using the vapor pressure balance method, designed to be compatible with Method A.4 Vapour Pressure of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 104 of the OECD Guidelines for Testing of Chemicals, 23 March 2006.