Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2011
Reliability:
1 (reliable without restriction)
Justification for type of information:
Testing was conducted using a procedure designed to be compatible with OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2011
Report Date:
2011

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
GLP compliance:
yes (incl. certificate)
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder
Details on test material:
White powder

Study design

Analytical method:
high-performance liquid chromatography

Results and discussion

Partition coefficient
Key result
Type:
log Pow
Partition coefficient:
ca. 1.071
Temp.:
25 °C
pH:
>= 5 - <= 9
Details on results:
Using the correlation log K/log Pow, the log Pow of the test item MEPHTAMN HCl was calculated as 1.071 +-0.004.
The experimentaly determined value is probably the result for the test item form, i.e. the hydrochloride.

Applicant's summary and conclusion

Conclusions:
Using the correlation log K/log Pow, the log Pow of the test item MEPHTAMN HCl was calculated as 1.071 +-0.004.