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EC number: 205-851-3 | CAS number: 156-38-7
Endpoint summary
Administrative data
Description of key information
Appearance / physical state / colour:
The physical appearance of p-hydroxyphenylacetic acid is observed to be a off white solid crystalline powder organic compound.
Melting point/ Freezing point:
The melting point of p-hydroxyphenylacetic acid is determined to be 152 °C.
Boiling point:
The boiling point of p-hydroxyphenylacetic acid is determined to be 120-130 °C at 0.01 mmHg pressure.
Density:
The density of chemical p-hydroxyphenylacetic acid was estimated to be 1.319 ± 0.06 g/cm3 at 20 °C and 760 mmHg pressure.
Particle size distribution (Granulometry):
The particle size distribution of p-hydroxyphenylacetic acid was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was determined to be in the range of 147 micron to 52 micron.
Vapour pressure:
The vapour pressure of p-hydroxyphenylacetic acid is estimated to be 0.0074 Pa (5.55E-05 mm Hg) at 25 °C.
Partition coefficient:
The octanol water partition coefficent log Pow of test chemical p-hydroxyphenylacetic acid (CAS no. 156-38-7) was determined to be 0.75 dimensionless. On the basis of this partition coefficient value it can be concluded that test chemical p-hydroxyphenylacetic acid (CAS no. 156-38-7) is hydrophilic in nature which is also supported by water solubility of test chemical.
Water solubility:
The water solubility of p-hydroxyphenylacetic acid is determined to 17300 mg/L at 22 °C.
Surface tension:
Based on the prediction done by ACD labs, the surface tension for chemical p-hydroxyphenylacetic acid was predicted to be 59.8 ± 3.0 dyne/cm.
Flash point:
The flash point of p-hydroxyphenylacetic acid was estimated as 177.6 ± 17.4 °C.
Autoflammability:
p-hydroxyphenylacetic acid did not catch fire on being exposed to air at room temperature of 27°C pressure of 966 hPa. This indicates that p-hydroxyphenylacetic acid is not auto-flammable.
Flammability:
p-hydroxyphenylacetic acid does not indicate any ignition when the flame of bunsen burner having temperature of approximately 950°C is brought in contact with it. Thus it can be concluded that p-hydroxyphenylacetic acid is not flammable at high temperature. However since such high temperatures are not found under normal circumstances of transportation and use, thus p-hydroxyphenylacetic acid was considered non-flammable for chemical safety assessment.
Explosiveness:
The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties.
Oxidising properties:
The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with oxidizing properties and hence the classification procedure does not need to be applied.
Additional information
Appearance / physical state / colour:
Based on available data from handbook and authoritative databases, the physical appearance of p-hydroxyphenylacetic acid is observed to be a off white solid crystalline powder organic compound.
Melting point/ Freezing point:
Based on available data from handbooks and authoritative databases, the melting point of p-hydroxyphenylacetic acid is determined to be 152 °C.
Other supporting data from authoritative database, also supported the selected key study and exhibited the melting point of p-hydroxyphenylacetic acid as 148-150 °C, closer to the selected key value.
Boiling point:
Based on available data from authoritative database Scifinder, the boiling point of p-hydroxyphenylacetic acid is determined to be 120-130 °C at 0.01 mmHg pressure.
Density:
Based on prediction done using ACD/I-Lab 2.0 and Scifinder, the density of chemical p-hydroxyphenylacetic acid was estimated to be 1.319 ± 0.06 g/cm3 at 20 °C and 760 mmHg pressure.
Particle size distribution (Granulometry):
The particle size distribution of p-hydroxyphenylacetic acid was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was determined to be in the range of 147 micron to 52 micron.
Vapour pressure:
Based on available data from authoritative databases, the vapour pressure of p-hydroxyphenylacetic acid is estimated to be 0.0074 Pa (5.55E-05 mm Hg) at 25 °C.
Partition coefficient:
The octanol water partition coefficent log Pow of test chemical p-hydroxyphenylacetic acid (CAS no. 156-38-7) was determined to be 0.75 dimensionless. On the basis of this partition coefficient value it can be concluded that test chemical p-hydroxyphenylacetic acid (CAS no. 156-38-7) is hydrophilic in nature which is also supported by water solubility of test chemical.
Water solubility:
Based on available data from authoritative database, the water solubility of p-hydroxyphenylacetic acid is determined to 17300 mg/L at 22 °C.
Other supporting data from handbook and authoritative database, also supported the selected key study and exhibited the water solubility of p-hydroxyphenylacetic acid as 160000 mg/L and 60700 mg/L at 25 °C respectively.
Hence on the basis of obtained values the given chemical is considered to be very soluble in water.
Surface tension:
Based on the prediction done by ACD labs Software (v12.1.0.50375), the surface tension for chemical p-hydroxyphenylacetic acid was predicted to be 59.8 ± 3.0 dyne/cm.
Flash point:
Based on available data from authoritative database Scifinder, the flash point of p-hydroxyphenylacetic acid was estimated as 177.6 ± 17.4 °C. Thus accroding to estimated value the given chemical was not classified as flammable.
Autoflammability:
p-hydroxyphenylacetic acid did not catch fire on being exposed to air at room temperature of 27°C pressure of 966 hPa. This indicates that p-hydroxyphenylacetic acid is not auto-flammable.
Flammability:
p-hydroxyphenylacetic acid does not indicate any ignition when the flame of bunsen burner having temperature of approximately 950°C is brought in contact with it. Thus it can be concluded that p-hydroxyphenylacetic acid is not flammable at high temperature. However since such high temperatures are not found under normal circumstances of transportation and use, thus p-hydroxyphenylacetic acid was considered non-flammable for chemical safety assessment.
Explosiveness:
The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties.
Oxidising properties:
The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with oxidizing properties and hence the classification procedure does not need to be applied.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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