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EC number: 946-604-6 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Boiling point
Administrative data
Link to relevant study record(s)
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From 9th May to 7th June 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- The study was conducted according to an internationally recognised method. The substance is considered to be adequately characterised. Therefore full validation applies.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 103 (Boiling Point)
- Version / remarks:
- 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- Version / remarks:
- 2008
- Deviations:
- no
- Principles of method if other than guideline:
- Not applicable
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- inspected on 13 and 14 October 2014 / signed on 08 April 2015
- Type of method:
- differential scanning calorimetry
- Key result
- Boiling pt.:
- ca. 96.22 °C
- Atm. press.:
- ca. 101 325 Pa
- Remarks on result:
- other: As the test item is an UVCB substance the lowest temperature value under these circum-stances will be stated as the initial boiling point for the possibly minor constituent as: 96.22 °C (369.37 K).
- Conclusions:
- The initial boiling point was determined as the lowest value under these circumstances as: 96.22 °C (369.37 K).
- Executive summary:
The study was performed in order to determine the boiling point of test item according OECD 103, resp. EU A.2 guideline, usind Differential Scanning Calorimetry.
Considering both the preliminary test according to Siwoloboff, and the two main DSC determinations, the first thermal event, recorded at 103.07°C and 96.22°C in the main test, is supposed related to the first bubbles and condensate observed with the capillary. Therefore, it is not considered representative of the substance (possibly minor constituent).
Thus, the result of the preliminary test according to Siwoloboff (boiling chain broke at 167 °C) and the second event of the main tests (197.26°C and 182.33°C) can be considered more representative of the substance.
The initial boiling point can be stated as the lowest value of the main DSC tests. The initial boiling point under these circumstances is therefore 96.22 °C (369.37 K)
with composition changes.
No observations were made which might cause doubts on the validity of the study outcome. Therefore, the result of the study is considered valid.
Reference
Pre-Test following Siwoloboff
Individual bubble was visible since 60 °C, a colourless condensate was noticed.
Constant bubbles were observed at 170 °C and a boiling chain at 172 °C. The heating was switched off at 182 °C. The boiling chain broke at 167 °C.
After cooling down no signs of changes were visible.
Security Pre-test for the DSC instrument
The crucible was heated up to 420°C. After cooling down the crucible was visual unchanged. The weight was recorded with 46.08 mg, then the crucible was heated to 600 °C. After cooling down the crucible was visual unchanged. The weight was recorded with 46.01 mg. After that the crucible was opened and no test item was visible.
Calibration
After
calibration with indium and zinc the measurement of indium yielded the
values:
Table.- Values DSC Indium
Expected Melting point |
Measured Melting point |
Expected Energy |
Measured Energy |
Assessment |
156.6 ± 1.0°C |
156.31 °C |
28.45 ± 1.0 J/g |
29.02 J/g |
OK |
The measurement of indium after calibration met the validity criteria.
DSC Measurement of the Test Item
First determination:
The peak in this measurement was caused through a contamination; therefore this determination will not be evaluated.
Second determination:
No event could be detected therefore the temperature range was adopted and more test item was used.
Third dertermination:
Temperature[°C] |
Energy |
|
First endothermic event |
103.07 (Onset) |
0.84[J/g] |
Second endothermic event |
197.26 |
14.92[J/g] |
Forth determination:
Temperature[°C] |
Energy |
|
First endothermic event |
96.22 (Onset) |
2.89[J/g] |
|
Temperature[°C] |
Heat Flow |
Second endothermic event |
182. 33 |
40.35[mW] |
Observations:
Mass test item |
Mass crucible (before measurement): |
Mass crucible (after measurement): |
Observations |
|
First Determination |
A contamination occurred; therefore this determination will not be evaluated. |
|||
Second Determination |
1.52 mg |
47.05 mg |
46.31 mg |
After the test the crucible was visually unchanged |
Third Determination |
2.20 mg |
48.15 mg |
45.96 mg |
After the test the crucible was visually unchanged |
Forth Determination |
2.01 mg |
48.24 mg |
46.36 mg |
After the test the crucible was visually unchanged |
Interpretation of the measurements:
Four determinations were performed.
The first determination can be discarded, because the measured peak was caused through contamination of the instrument.
No event could be detected in the second determination, therefore the temperature range was adapted and more test item was used.
The third determination showed three endothermic events. Only the first two events were evaluated because the last event can be related to a decomposition product.
Both events were evaluated with the “onset” function.
The forth determination, where less test item than in the third determination was used, showed three endothermic events as well. Also only the first two events were evaluated because the last event can be related to a decomposition product. The first and third event are endothermic and the second slightly exothermic. The first event was evaluated with the “onset” function. The second event only could be evaluated with the “event marker” function.
In the Pre-test following Siwoloboff a colourless condensate was noticed at >60 °C. Boiling was observed at 170 °C, the boiling chain broke at 167 °C.
Based on these facts the first event of the second and third determination can be related to colourless condensate.
The first event might be partial evaporation of one constituent.
As the test item is an UVCB substance the lowest temperature value under these circumstances should be stated as the initial boiling point with composition changes.
Presentation of results
Table.- Values DSC measurements
in °C |
in K |
|
1Determination |
Not evaluated through contamination |
|
2Determination |
No Event |
|
3Determination |
|
|
1 Event |
103.07 |
376.22 |
2 Event |
197.26 |
470.41 |
4Determination |
|
|
1 Event |
96.22 |
369.37 |
2 Event |
182.33 |
455.48 |
Validity
As decomposition was stated no valid criteria need to consider.
Discussion
The boiling point was determined via DSC (differential scanning calorimetry).
Considering the test item is an UVCB substance, the transition is expected to vary from batch-to-batch, therefore it is considered more appropriate to express the final result as an approximate initial boiling point, instead of a range, considering the range would apply to the present batch only, and is not specifications, which is the responsibility of the manufacturer.
Considering both the preliminary test according to Siwoloboff, and the two main DSC determinations, the first thermal event, recorded at 103.07°C and 96.22°C in the main test, is supposed related to the first bubbles and condensate observed with the capillary. Therefore, it is not considered representative of the substance (possibly minor constituent).
Thus, the result of the preliminary test according to Siwoloboff (boiling chain broke at 167 °C) and the second event of the main tests (197.26°C and 182.33°C) can be considered more representative of the substance.
The initial boiling point can be stated as the lowest value of the main DSC tests. The initial boiling point under these circumstances is therefore 96.22 °C (369.37 K)
with composition changes.
No observations were made which might cause doubts on the validity of the study outcome. Therefore, the result of the study is considered valid.
Description of key information
The initial boiling point was determined as the lowest value under these circumstances as: 96.22 °C (369.37 K)
Key value for chemical safety assessment
- Boiling point at 101 325 Pa:
- 96.22 °C
Additional information
A fully reliable experimental study, conducted according to OECD 103/ EU A2 guideline is available.
It is considered as a key study, and the result is retained as key data.
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