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EC number: 211-105-8
CAS number: 629-73-2
an acute inhalation toxicity study, a limit test was first performed on
a group of 10 young male adult Sprague-Dawley rats. The animals were
exposed to 87.5
1-octene for one hour. After one hour of exposure nine out of ten
animals were found dead. Following the limit test a four hour LC50
inhalation toxicity study was performed on 6 groups, 10 per group, of
male Sprague-Dawley rats which were exposed to 1octene, whole body, by
inhalation route for four hours (vapour atmosphere) at exposure
concentrations of 28.0, 31.1, 36.0,
40.5, 48.4, and 53.6 mg/L. Based on the results study authors concluded
that the LC50 for 1-octene in male Sprague-Dawley rats for a four hour
exposure period is 8050
parts per million, with a 95% confidence interval of 6600-9800 parts per
study was given a Klimisch score of 2 and was classified as reliable
with restrictions because while this study predates GLP guidance, the
limited information provided indicates that this study was conducted in
a manner similar to OECD 403 guideline.
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