Registration Dossier
Registration Dossier
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EC number: 235-049-9 | CAS number: 12062-81-6
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- migrated information: read-across based on grouping of substances (category approach)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: short report - test was conducted with (Fe, Mn)3O4 (CAS 68186-94-7) as a surrogate for (Fe,Mn)2O3
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 977
- Report date:
- 1977
Materials and methods
- Principles of method if other than guideline:
- single oral application per gavage, observation time 14 days
- GLP compliance:
- not specified
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- Manganese ferrite black spinel
- EC Number:
- 269-056-3
- EC Name:
- Manganese ferrite black spinel
- Cas Number:
- 68186-94-7
- Molecular formula:
- (Fe,Mn)3O4
- IUPAC Name:
- manganese ferrite black spinel
- Test material form:
- solid: particulate/powder
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- male
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- water
- Doses:
- 10000 mg/kg bw
- No. of animals per sex per dose:
- 10
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- male
- Dose descriptor:
- LD50
- Effect level:
- > 10 000 mg/kg bw
- Clinical signs:
- other:
Any other information on results incl. tables
no mortality, no symptoms
Applicant's summary and conclusion
- Executive summary:
- Single oral application per gavage, observation time 14 days
Result: no symptoms, no mortality
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