Registration Dossier
Registration Dossier
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EC number: 213-552-4 | CAS number: 976-70-5
Endpoint summary
Administrative data
Description of key information
Additional information
The aquatic toxicity was studied in an acute immobilization test with Daphnia magna according to test guideline OECD 202. The daphnids were exposed over 48 hours to 5 concentrations of the test substance between 2.8 and 29.8 mg/L, measured by TOC analysis and a control. There was a concentration related immobilization. The EC50/24h of aldona was higher than 29.8 mg/L, the EC50/48 hours was determined with 26.9 mg/L. The NOEC/48h was 16.6 mg/L, the LOEC/48h was 29.8 mg/L. The study was conducted according to GLP (see Schering report no. A03236).
The aquatic toxicity of aldona was also studied in a algal growth inhibition test with the green algae Selenastrum capricornutum according to the test guideline OECD 201. The algae were incubated with the test compound over a period of 72 hours in 5 concentrations between 3.2 and 33.8 mg/L, measured by TOC analysis, and a control. In the highest concentration, the griwth rate was significantly reduced, although less than 50%. Therefore, the ErC50/72h was higher than 33.8 mg/L, the NOEC was 18.8 mg/L, the LOEC 33.8 mg/L. The study was conducted according to GLP (see Schering report no. A03237)
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