Registration Dossier
Registration Dossier
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EC number: 944-528-8 | CAS number: -
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
The hydrolysis study according to OECD 111 resulted in hydrolysis < 10% after 5 d at pH 7 and 9 and 50 °C. Thus, a DT50 > 1 yr at pH 7 and 9 (25 °C) was extrapolated in accordance with the guideline. A main test was performed for pH 4 at 20, 30 and 50 °C for 31 d resulting in DT50 values of 384 d (20 °C), 78.7 d (30 °C) and 13.7 d (50 °C). Thus, the substance hydrolyses slowly under environmental conditions.
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 1 yr
- at the temperature of:
- 25 °C
Additional information
One experimental study was performed according to OECD 111 (GLP).
A preliminary test with a concentration of approx. 250 mg/L was
performed at 3 different pH values (pH 4, 7 and 9) and 50 °C for 120 h.
The result from HPLC-DAD analysis indicated that the test substance is
hydrolytically stable at pH 7 and 9 at 50 °C. Recovery of the substance
at pH7 and pH9 was 96.15% and 100%, respectively. Thus, in accordance
with the guideline no main test was considered necessary for pH 7 and 9
and the results from the preliminary test were extrapolated to 25 °C. At
25 °C the DT50 of the test substance was estimated to be > 1 yr at pH 7
and 9.
At pH 4 only 63.2% of the substance was found after 120 h in the
preliminary test. Since hydrolysis was > 10% for pH4 a main test at
three different temperatures (20, 30 and 50 °C) was performed. After 31
d DT50 values of 384 d (20 °C), 78.7 d (30 °C) and 13.7 d (50 °C)
resulted. In conclusion, the test substance hydrolyses slowly under
environmental conditions.
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