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EC number: 405-290-6 | CAS number: 12036-37-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 9 March 1990 - 26 March 1990
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study conducted to GLP in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results.
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- yes
- Remarks:
- See below
- Principles of method if other than guideline:
- The guideline states that the test material should be dissolved in a suitable solvent and coated onto the support material. No suitable solvent could be found and so the test material was dry mixed with the support material.
This deviation was not considered to affect the validity of the study or the results. - GLP compliance:
- yes
- Type of method:
- column elution method
- Water solubility:
- 13 mg/L
- Temp.:
- 20 °C
- pH:
- 7.6
- Details on results:
- In the first determination (A), it was apparent that saturation was not reached, even after 98 hours; these values were not used to calculate the water solubility.
In the second determination (B), saturation was reached after 54 hours (Sample Number B6) and the values from sample numbers B6, B7, B8, B9 and B10 were used to calculate the water solubility.
Mean of B6, B7, B8, B9 and B10 = 13 mg/L
Range = 11.7 to 13.6 mg/L
Standard deviation = 0.000733 - Conclusions:
- Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The water solubility was determined to be 13 mg/L at 20.0 ± 0.5 °C. - Executive summary:
A study was carried out to determine the water solubility of the test material in accordance with the standardised guideline EU Method A.6.
The investigation was carried out using the column elution method with a recirculating pump and the water solubility was determined to be 13 mg/L at 20.0 ± 0.5 °C.
Reference
Table 1 Summary of Results
Sample Number |
Sampling Time (hours) |
Concentration of Test Material (mg/L) |
Solution pH |
A1 A2 A3 A4 A5 A6 A7 A8 A9 A10 A11 |
3 24 27 29 48 52 54 72 73 97 98 |
5.15 8.78 8.51 8.88 9.09 9.51 9.62 10.2 10.6 12.3 12.0 |
7.6. 7.2 8.1 8.2 7.8 7.8 7.8 7.5 7.6 7.6 7.5 |
B1 B2 B3 B4 B5 B6 B7 B8 B9 B10 |
24 27 29 48 52 54 72 73 97 98 |
9.09 9.35 9.56 10.3 12.5 13.1 13.1 11.7 13.3 13.6 |
7.2 8.2 8.2 7.8 7.9 7.8 7.6 7.6 7.6 7.6 |
Description of key information
The water solubility was determined to be 13 mg/L at 20.0 ± 0.5 °C.
Key value for chemical safety assessment
- Water solubility:
- 13 mg/L
- at the temperature of:
- 20 °C
Additional information
A study was carried out to determine the water solubility of the test material in accordance with GLP and the standardised guideline EU Method A.6.
The investigation was carried out using the column elution method with a recirculating pump and the water solubility was determined to be 13 mg/L at 20.0 ± 0.5 °C.
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