1,1,2,2,3,3,4,4-octafluoro-1,4-diiodobutane

Density

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

relative density

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From September 2017 to December 2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.3 (Relative Density)

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7300 (Density / Relative Density / Bulk Density)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

pycnometer method

Specific details on test material used for the study:

- Appearance: Pink liquid
- Test item storage: At room temperature protected from light
- Purity/Composition correction factor: No correction factor required

Key result

Type:

relative density

Density:

2.5 other: dimensionless

Temp.:

20 °C

Remarks on result:

other: mean value

Type:

density

Density:

2.5 g/cm³

Temp.:

20 °C

Remarks on result:

other: mean value

The individual measurements were obtained with an accuracy of < 0.01 g/cm³. In according with the guideline, the density of the test item is thus given as the mean value.

Conclusions:

The mean density of the test item was 2.50 g/cm3 at 20°C; the mean relative density was 2.50.

Executive summary:

The relative density of the test item was determined in a GLP-compliant study performed in accordance with EC A.3 Method and OECD Guideline No. 109, using the pycnometer method. The mean density of the test item was 2.50 g/cm3 at 20°C; the mean relative density was 2.50.

Reference 2

Endpoint:

density

Remarks:

density

Type of information:

other: literature data

Adequacy of study:

supporting study

Study period:

2012

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

documentation insufficient for assessment

Qualifier:

no guideline followed

Principles of method if other than guideline:

No information available

GLP compliance:

no

Type:

density

Density:

2.41 g/cm³

Temp.:

20 °C

Conclusions:

A density of 2.41 g/cm3 at 20 °C was reported for DIOFB.

Executive summary:

Only the result was reported and no information about the method used was provided; therefore the reliability of the data is not assignable.

Reference 3

Endpoint:

relative density

Type of information:

other: literature data

Adequacy of study:

supporting study

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

documentation insufficient for assessment

Qualifier:

no guideline followed

Principles of method if other than guideline:

No information available

GLP compliance:

no

Type:

relative density

Density:

2.474

Temp.:

27 °C

Remarks on result:

other: relative to water at 4 °C

Type:

relative density

Density:

2.547

Temp.:

0 °C

Remarks on result:

other: relative to water at 4 °C

Conclusions:

Relative densities of 2.4739 at 27 °C/4 °C and 2.5466 at 0 °C/4 °C were reported for DIOFB.

Executive summary:

Only the results were reported and no information about the method used was provided; therefore the reliability of the data is not assignable.

Reference 4

Endpoint:

relative density

Type of information:

other: literature data

Adequacy of study:

supporting study

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

documentation insufficient for assessment

Qualifier:

no guideline followed

Principles of method if other than guideline:

No information available

GLP compliance:

no

Type:

relative density

Density:

2.491

Temp.:

20 °C

Remarks on result:

other: relative to water at 4 °C

Conclusions:

A specific gravity of 2.491 (20 °C/4 °C) was reported for DIOFB.

Executive summary:

Only the result was reported and no information about the method used was provided; therefore the reliability of the data is not assignable.

Reference 5

Endpoint:

density

Remarks:

density

Type of information:

other: literature data

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

documentation insufficient for assessment

Remarks:

Literature data coming from public article without sufficient documentation for reliability assessment

Guideline:

other: no guideline was specified in the different literature data

GLP compliance:

not specified

Type of method:

other: no data

Type:

density

Density:

2.487 g/cm³

Temp.:

20 °C

Conclusions:

The density of the test substance was found to be 2.4870 at 20°C.

Executive summary:

A literature data gives a density of 2.4870 at 20°C for this test substance.

Reference 6

Endpoint:

relative density

Type of information:

other: literature data

Adequacy of study:

supporting study

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

documentation insufficient for assessment

Qualifier:

no guideline followed

Principles of method if other than guideline:

No information available

GLP compliance:

no

Type:

relative density

Density:

2.487

Temp.:

25 °C

Conclusions:

A relative density of 2.487 at 25 °C was reported for DIOFB.

Executive summary:

Only the result was reported and no information about the method used was provided; therefore the reliability of the data is not assignable.

Reference 7

Endpoint:

density

Remarks:

density

Type of information:

other: literature data

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

documentation insufficient for assessment

Remarks:

Literature data coming from public database without sufficient documentation for reliability assessment

Guideline:

other: no guideline was specified in the different literature data

GLP compliance:

not specified

Type of method:

other: method not specified

Type:

density

Density:

2.491 g/cm³

Temp.:

25 °C

Remarks on result:

other: Data coming from:"Yaws' Handbook of Physical Properties for Hydrocarbons and Chemicals 2008"

Type:

density

Density:

2.491 g/cm³

Temp.:

25 °C

Remarks on result:

other: Data ccoming from: "Yaws' Critical Property Data for Chemical Engineers and Chemists 2012"

Type:

density

Density:

2.474 g/cm³

Remarks on result:

other: Temperature not specified. Data coming from "Knovel Critical Tables (2nd Edition) 2008"

Three references (coming from the same database) have been found for the density of the test substance. One density value was considered less reliable than the two others, because the temperature at which this value was determined was not specified.

That's why the density of the test substance is considered to be 2.4912 g/cm³ at 25°C

Conclusions:

The density of the test substance is 2.4912g/cm3 at 25°C.

Executive summary:

Two literature references (obtained in the same database) give the same value for the density of the test substance: 2.4912 g/cm³at 25°C

Description of key information

The relative density of the test item was determined in a GLP-compliant study performed in accordance with EC A.3 Method and OECD Guideline No. 109, using the pycnometer method. The mean density of the test item was 2.50 g/cm3 at 20°C; the mean relative density was 2.50. These experimental values are further supported by data from the literature.

Key value for chemical safety assessment

Relative density at 20C:

2.5

Additional information

The relative density of the test item was determined in a GLP-compliant study performed in accordance with standard methods, without deviations. The study is considered as reliable (Klimisch 1) and is selected as a key study for the endpoint. Literature data are also reported for the endpoint and selected as supporting studies (Klimisch 4).