Registration Dossier

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2013
Report date:
2013

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
GLP compliance:
yes
Type of method:
isoteniscope

Test material

Constituent 1
Details on test material:
- Purity: > 96%

Results and discussion

Vapour pressureopen allclose all
Temp.:
20 °C
Vapour pressure:
0.21 kPa
Temp.:
25 °C
Vapour pressure:
0.28 kPa
Transition / decomposition
Transition / decomposition:
no

Applicant's summary and conclusion

Conclusions:
Vapour Pressure was determined to be 0.21 kPa and 0.28 kPa at 20 and 25°C, respectively.
Executive summary:

Vapour pressure of the test substance was determined according to OECD Guideline 104. The measuring principle is equivalent to ASTM D2879-86 (isoteniscope principle) but with only 1 mL sample volume. The instrument consisted of a vacuum-sealed measuring chamber of an overall volume of 5 mL. A piezoresistive pressure transducer was integrated in the vacuum chamber. A vacuum valve was installed in the chamber for automatic outgassing of the sample. Cooling and heating was performed with a Peltier element. The vapour pressure as a function of temperature was registered in 20-100°C range in 5°C steps.

The vapour pressure curve (log p versus 1/T) was plotted. A line was fitted to the measured data (above 0.5 kPa) applying the least squares method with the help of Excel for Windows software. Based on the simplified Clausius-Clapeyron equation a regression line was fitted on the measured data and the vapour pressure was extrapolated for 20 and 25°C.

 

The vapour pressure was 0.21 kPa at 20°C and 0.28 kPa at 25°C.