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EC number: 943-428-1 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.2 mg/L
- Assessment factor:
- 50
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 0.179 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.02 mg/L
- Assessment factor:
- 500
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- no hazard identified
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 7.11 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.711 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 1.305 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Conclusion on classification
According to Article 13 of Regulation (EC) No 1907/2006 "General Requirements for Generation of Information on Intrinsic Properties of Substances", Information on intrinsic properties of substances may be generated by means other than tests e.g. from information from structurally related substances (grouping or read-across), provided that conditions set out in Annex XI are met. Annex XI, "General rules for adaptation of this standard testing regime set out in Annexes VII to X” states that “substances whose physicochemical, toxicological and ecotoxicological properties are likely to be similar or follow a regular pattern as a result of structural similarity may be considered as a group, or ‘category’ of substances. This avoids the need to test every substance for every endpoint”. Since the read-across concept is applied for selected endpoint, data will be generated from a representative source substance to avoid unnecessary animal testing. Additionally, once the read-across concept is applied, substances will be classified and labelled on this basis.
Brief description of the data relevant for classification
Degradation:
Biodegradation: readily biodegradable: 62.5% to 88% after 28 d (OECD 301 C and F); read-across
Bioaccumulation:
Low potential for bioaccumulation.
Aquatic acute toxicity
Fish:
· RA CAS 1338-41-6: LL50 (96 h, Oryzias latipes) > 1000 mg/L (nominal, WAF)
· RA CAS 1338-39-2: LC50 (96 h, Danio rerio) > 100 mg/L (nominal)
· RA CAS 9005-64-5: LL50 (96 h, Danio rerio) > 100 mg/L (nominal)
Aquatic invertebrates:
· RA CAS 1338-41-6: EL50 (48 h, Daphnia magna) >1000 mg test item/L (nominal)
· RA CAS 1338-39-2: LL50 (48 h, Acartia tonsa) = 452.84 mg test item/L (nominal, WAF)
Algae:
· RA CAS 1338-41-6: EL50 (72 h, Pseudokirchneriella subcapitata) >1000 mg/L (nominal, WAF, based on growth rate)
· RA CAS 1338-39-2: EL50 (72 h, Skeletonema costatum) = 17.89 mg/L (nominal, WAF, based on growth rate)
· RA CAS 9005-64-5: EL50 (72 h, Pseudokirchnerella subcapitata) = 58.84 mg/L (nominal, WAF, based on growth rate)
Aquatic chronic toxicity
Fish: no data available
Aquatic invertebrates:
· RA CAS 1338-41-6: NOELR (21 d, Daphnia magna) ≥ 16 mg/L (nominal, based on cumulative number of juveniles produced per adult
· RA CAS 9005-64-5: NOELR (21, Daphnia magna) = 10 mg/L (nominal, WAF)
Algae:
· RA CAS 1338-41-6: NOELR (72 h, Pseudokirchneriella subcapitata) = 560 mg/L (nominal, WAF, based on growth rate)
· RA CAS 1338-39-2: NOELR (72 h, Skeletonema costatum) ≥ 10 mg/L (nominal, WAF, based on growth rate)
· RA CAS 9005-64-5: EL10 (72 h, Pseudokirchnerella subcapitata) = 19.05 mg/L (nominal, WAF, based on growth rate)
Conclusion on classification
CLP:
Based on the data above, sorbitan C16-18 (even numbered) fatty acid esters, ethoxylated (1-6.5 moles ethoxylated) is considered to be rapidly biodegradable. The acute aquatic toxicity L(E) C(L)50 values are ≥17.89 mg/L. Chronic toxicity data are additionally available for aquatic invertebrates and algae. The lowest NOELR value is 10 mg/L. Therefore, sorbitan C16-18 (even numbered) fatty acid esters, ethoxylated (1-6.5 moles ethoxylated) does not need to be classified and labelled for acute or long-term hazards to the aquatic environment according to the 6th ATP of the Regulation (EC) No 1272/2008 (CLP).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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