Registration Dossier
Registration Dossier
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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 460-450-2 | CAS number: 872728-82-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Guidance on Safe Use
Administrative data
First-aid measures
Emergency measure - Inhalation: Administration of oxygen or fresh air. Seek medical
attention. Medical supervision for at least 48 hours.
Emergency measure - Eyes: Flush with copious amounts of water under open eyelid for
several minutes. Protect unaffected eye. Seek medical
attention. Medical supervision for at least 48 hours.
Emergency measure - Skin: Wash affected areas with copious amounts of water. Take off
contaminated clothing immediately. Seek medical attention.
Medical supervision at least 48 hours.
Emergency measure - Ingestion: Rinse mouth with water. Afterwards drink plenty amounts of
water. Seek medical attention. Medical supervision for at
least 48 hours.
Fire-fighting measures
Recommended extinguishing agent: Adjust extinguishing operations according to the
environment.
Water, dry powder, foam and carbon dioxide (CO2).
Product arising from burning: Residues of combustion and contaminated water for fire
protection have to be disposed according to competent
authority regulations.
Product determined by test: N
Protective equipment: Circulating air independent respirator.
Avoid inhaling of evolving explosion and fire gases.
Accidental release measures
Emergency measures in case of spillage: Keep unprotected persons away.
Remove all sources of ignition.
Avoid dust formation when taking up mechanically by
using an appropriate vacuum cleaner.
Wear personnel protective equipment (see section
"Handling").
Do not release to surface water or drains.
Handling and storage
BIBR 1048 oxa-acid is handled under Strictly Controlled Conditions in accordance with REACH regulation Article 17(3) for on-site isolated intermediates and, in case the substance is transported to other sites for further processing, the substance should be handled at these sites under the Strictly Controlled Conditions as specified in REACH regulation Article 18(4). Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at each manufacturing site.
BIBR 1048 oxa-acid is handled under Strictly Controlled Conditions as defined under REACH Article 18(4) throughout its life cycle.
Specifically the substance is rigorously contained by technical means during its whole lifecycle; procedural and control technologies are used to minimise emissions and any resulting exposures; only properly trained and authorised personnel handle the substance; special procedures such as purging and washing are applied during cleaning and maintenance works, in cases of accident and where waste is generated, proceduraland/or control technologies are used to minimise emissions and the resulting exposures; and substance-handling procedures are well documented and strictly supervised by the site operator.
Transport information
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Marine transport (UN RTDG/IMDG)
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Exposure controls / personal protection
BIBR 1048 oxa-acid is handled under Strictly Controlled Conditions in accordance with REACH regulation Article 17(3) for on-site isolated intermediates and, in case the substance is transported to other sites for further processing, the substance should be handled at these sites under the Strictly Controlled Conditions as specified in REACH regulation Article 18(4). Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at each manufacturing site.
BIBR 1048 oxa-acid is handled under Strictly Controlled Conditions as defined under REACH Article 18(4) throughout its life cycle.
Specifically the substance is rigorously contained by technical means during its whole lifecycle; procedural and control technologies are used to minimise emissions and any resulting exposures; only properly trained and authorised personnel handle the substance; special procedures such as purging and washing are applied during cleaning and maintenance works, in cases of accident and where waste is generated, proceduraland/or control technologies are used to minimise emissions and the resulting exposures; and substance-handling procedures are well documented and strictly supervised by the site operator.
Stability and reactivity
Disposal considerations
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.