Registration Dossier
Registration Dossier
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EC number: 203-313-2 | CAS number: 105-60-2
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
As acute test on fish as well as acute and chronic test on algae and invertebrates reveal a low hazard potential of epsilon-Caprolactam, a chronic fish study is scientifically unjustified. Therefore, and for reasons of animal welfare, a long-term toxicity study in fish is not provided.
Key value for chemical safety assessment
Additional information
In Annex IX of Regulation (EC) No 1907/2006, it is laid down that chronic tests shall be proposed by the registrant if the chemical safety assessment indicates the need to investigate further the effects on fish.
According to Annex I of this regulation, the chemical safety assessment triggers further action when the substance or the preparation meets the criteria for classification as dangerous according to Directive 67/548/EEC or Directive 1999/45/EC or is assessed to be a PBT or vPvB. The hazard assessment of e-caprolactam reveals neither a need to classify the substance as dangerous to the environment, nor is it a PBT or vPvB substance, nor are there any further indications that the substance may be hazardous to the environment. Therefore, and for reasons of animal welfare a chronic test on fish is not provided. Furthermore, respective exposure scenarios are not calculated.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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