Registration Dossier
Registration Dossier
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EC number: 200-001-8 | CAS number: 50-00-0
Mode of degradation in actual use
Administrative data
- Endpoint:
- mode of degradation in actual use
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Remarks:
- Non guideline study investigating the mechanism of degradation
Data source
Reference
- Reference Type:
- publication
- Title:
- Mechanism of formaldehyde biodegradation by Pseudomonas putida.
- Author:
- Adroer N, Casas C, de Mas C, Sola C
- Year:
- 1 990
- Bibliographic source:
- Appl. Microbiol. Biotechnol. 33, 217-220
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
Test material
- Reference substance name:
- Formaldehyde
- EC Number:
- 200-001-8
- EC Name:
- Formaldehyde
- Cas Number:
- 50-00-0
- Molecular formula:
- CH2O
- IUPAC Name:
- formaldehyde
- Details on test material:
- - Name of test material (as cited in study report): formaldehyde
Constituent 1
Results and discussion
Any other information on results incl. tables
The mechanism of formaldehyde degradation by Pseudomonas putida is initiated by a dismutation reaction, yielding formic acid and methanol as products. Degradation of the products began after exhaustion of formaldehyde in the medium.
Applicant's summary and conclusion
- Conclusions:
- The mechanism of formaldehyde degradation by Pseudomonas putida is initiated by a dismutation reaction, yielding formic acid and methanol as products
- Executive summary:
The biodegradation of the test item was tested by a strain of Pseudomonas putida without following a guideline. The results indicate that this biodegradation is initiated by a dismutation reaction, yielding as products formic acid and methanol. The degradation of methanol and formic acid
begins after exhaustion of formaldehyde in the medium, and presents a diauxic pattern: first formic acid
is consumed followed by methanol. Moreover, cell viability, which is affected by the amount of added formaldehyde, has been determined.
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