Registration Dossier
Registration Dossier
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EC number: 232-051-1 | CAS number: 7784-18-1
Endpoint summary
Administrative data
Description of key information
Additional information
In a series of studies to test for the potential aquatic toxicity of aluminium fluoride (AlF3) was only slightly soluble in aqueous solution at a loading concentration of 1000 mg/L. Therefore, in each study, the undiluted water phase from the AlF3 mixture was set to 100% v/v, which was used as the high-concentration for testing in studies conducted in fish, daphnids, and algae. Dilutions also were tested in algae and microorganisms.
AlF3 was reported to have low acute toxicity to fish. The 96-hour NOEC for acute toxicity to zebra fish was determined to be 100% (v/v) (undiluted water phase of a loading of 1000 mg/L of AlF3), which was equivalent to 7.6 mg fluoride/L, in an OECD guideline study (Test No. 203) (Olsson, 2001). Additionally, the 96-hour EC50 was determined to be greater than 7.6 mg fluoride/L.
AlF3 also was reported to have low acute toxicity to an aquatic invertebrate species. The 48-hour NOEC for acute toxicity in Daphnia magna was determined to be 100% (v/v) (undiluted water phase of a loading of 1000 mg/L of AlF3), which was equivalent to 7.6 mg fluoride/L, in an OECD guideline study (Test No. 202) (Olsson, 2001). Additionally, the 48-hour EC50 was determined to be greater than 7.6 mg fluoride/L.
AlF3 was reported to have low acute toxicity to algae. Slight growth inhibition was observed in Selenastrum capricornutum as assessed in an OECD guideline study (Test No. 201) (Olsson, 2001). The growth inhibition was reported to be most likely due to fluoride exposure. The 72-hour NOEC for growth rate inhibition was determined to be 22.5% (v/v) (undiluted water phase of a loading of 1000 mg/L of AlF3), which was equivalent to 1.7 mg fluoride/L. In addition, the 72-hour EC10 for growth rate inhibition was determined to be 1.8 mg fluoride/L and the 72-hour EC50 and EC90 for growth rate inhibition both greater than 1.8 mg fluoride/L.
AlF3 was reported to have low toxicity to microorganisms derived from activated sludge, with a 3-hour EC50 value for growth inhibition of greater than 50% (v/v) in an OECD guideline study (Test No. 209) (Carlsson, 2002).
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