Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 206-114-9 | CAS number: 302-01-2
Neurotoxicity
Administrative data
- Endpoint:
- neurotoxicity
- Remarks:
- other: in vitro
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: special in-vitro investigations
Data source
Referenceopen allclose all
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 988
- Report date:
- 1988
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 990
- Report date:
- 1990
- Reference Type:
- other: status report
- Title:
- Unnamed
- Year:
- 1 991
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 993
- Report date:
- 1993
Materials and methods
- Principles of method if other than guideline:
- in vitro investigations
- GLP compliance:
- no
Test material
- Reference substance name:
- Hydrazine
- EC Number:
- 206-114-9
- EC Name:
- Hydrazine
- Cas Number:
- 302-01-2
- Molecular formula:
- H4N2
- IUPAC Name:
- hydrazine
- Details on test material:
- no further data
Constituent 1
Test animals
- Species:
- other: in vitro investigation
- Strain:
- other: in vitro investigation
Administration / exposure
- Route of administration:
- other: in vitro investigatioj
- Duration of treatment / exposure:
- in vitro investigations
- Frequency of treatment:
- in vitro investigations
- No. of animals per sex per dose:
- in vitro investigations
Results and discussion
Effect levels
- Dose descriptor:
- other:
- Basis for effect level:
- other: in vitro investigation
- Remarks on result:
- not measured/tested
- Remarks:
- Effect level not specified Generation: other: - null (migrated information)
Any other information on results incl. tables
the effects of hydrazines on neuronal excitability is investigated in in-vitro experiments
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
