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Ecotoxicological information

Toxicity to birds

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Description of key information

Toxicity to predators via secondary poisoning is not expected for Fatty acids C16-18, methyl esters 

Key value for chemical safety assessment

Additional information

No avian toxicity data are available for Fatty acids C16-18, methyl esters (CAS No. 85586-81-6). According to Regulation (EC) No. 1907/2006, Annex X, Column 2, 9.6.1, any need for testing for this endpoint should be carefully considered taking into account the large mammalian dataset that is usually available at this tonnage level. Fatty acids C16-18, methyl esters is a readily biodegradable substance with a low potential for bioaccumulation in biota (see section 5.3) and therefore, according to the Guidance on information requirements and chemical safety assessment, Chapter R.7C, secondary poisoning is unlikely to occur (ECHA, 2008). The results of the repeated dose oral tests performed on mammals (analogue substance, see section 7.5) showed no toxic effects after an exposure of 28 days (NOAEL of 1000 mg/kg bw/day (JECDB, 2000)). The test substance is not classified either for the environment or as Very Toxic (T+) or Toxic (T) or harmful (Xn) with at least one of the risk phrases R48 “Danger of serious damage to health by prolonged exposure”, R60 “May impair fertility”, R61 “May cause harm to the unborn child”, R62 “Possible risk of impaired fertility”, R63 “Possible risk of harm to the unborn child”, R64 “May cause harm to breastfed babies”, and therefore it is considered not to possess a potential to cause toxic effects if accumulated via the food chain.

Based on the above information and considering animal welfare, avian toxicity testing is not deemed necessary for Fatty acids C16-18, methyl esters (CAS No. 85586-81-6).