Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 203-401-0 | CAS number: 106-47-8
Long-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Acceptable, well documented publications which meet basic scientific principles
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Schadstoffwirkungen von Umweltchemikalien im Daphnien- Reproduktionstest als Grundlage zur Bewertung der Umweltgefährlichkeit in aquatischen Systemen
- Author:
- Kühn R, Pattard M, Pernak K-D, Winter A
- Year:
- 1 988
- Bibliographic source:
- Prepared by Institut für Wasser-, Boden- und Lufthygiene des Bundesgesundheitsamtes, Berlin, for Umweltbundesamt, 412 pp. (Report No. 10603052)
- Reference Type:
- publication
- Title:
- Results of the harmful effects of water pollutants to Daphnia magna in the 21 day reproduction test
- Author:
- Kühn R, Pattard M, Pernak KD, Winter A
- Year:
- 1 989
- Bibliographic source:
- Water Research, 23:501¿510
- Reference Type:
- review article or handbook
- Title:
- p-Chloranilin
- Author:
- Gesellschaft Deutscher Chemiker (GDCh)
- Year:
- 1 993
- Bibliographic source:
- Beratergremium für umweltrelevante Altstoffe (BUA). Wissenschaftliche Verlagsgesellschaft, BUA-Stoffbericht 153
Materials and methods
- Principles of method if other than guideline:
- 21 days - Reproduction test with Daphnia magna in accordance with national standards (Federal Environmental Agency, Germany)
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 4-chloroaniline
- EC Number:
- 203-401-0
- EC Name:
- 4-chloroaniline
- Cas Number:
- 106-47-8
- Molecular formula:
- C6H6ClN
- IUPAC Name:
- 4-chloroaniline
- Details on test material:
- - Name of test material (as cited in study report): p-Chloroaniline
- Analytical purity: no data
Constituent 1
Test solutions
- Details on test solutions:
- synthetic test medium (DIN, German Institute of Standardization, 1982)
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- < 24 h old
Study design
- Test type:
- semi-static
- Water media type:
- freshwater
- Total exposure duration:
- 21 d
Test conditions
- Test temperature:
- 25 ± 1
- pH:
- 8.0 ± 2
Results and discussion
Effect concentrations
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.01 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
