Registration Dossier
Registration Dossier
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EC number: 269-798-8 | CAS number: 68333-89-1 The non-volatile, high-boiling residue from the distillation of products from cumene-phenol process. It consists predominantly of substituted phenyl groups crosslinked by carbon-oxygen bonds and phenylaliphatic bonds.
Bioaccumulation: aquatic / sediment
Administrative data
- Endpoint:
- bioaccumulation: aquatic / sediment
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: generally accepted calculation method
Data source
Reference
- Reference Type:
- other: unpublished calculation
- Title:
- Unnamed
- Year:
- 2 007
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The bioconcentration factor BCF was calculated using EPIWIN v3.20, BCFWIN v2.17.
- GLP compliance:
- no
Test material
- Reference substance name:
- Acetophenone
- EC Number:
- 202-708-7
- EC Name:
- Acetophenone
- Cas Number:
- 98-86-2
- Molecular formula:
- C8H8O
- IUPAC Name:
- 1-phenylethanone
Constituent 1
Test organisms
- Test organisms (species):
- other: fish
Test conditions
- Details on estimation of bioconcentration:
- BASIS FOR CALCULATION OF BCF
- Estimation software: EPIWIN v3.20, BCFWIN v2.17
- Result based on measured log Pow of: 1.58
Results and discussion
Bioaccumulation factor
- Type:
- BCF
- Value:
- 0.475
Any other information on results incl. tables
The bioconcentration factor BCF was calculated using EPIWIN v3.20, BCFWIN v2.17. The estimation yielded a BCF of 0.4749. Based on the result, it can be assumed that acetophenone will bioconcentrate in fish only to a minor degree.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- Based on the estimation (BCF=0.4749) , it can be assumed that acetophenone will bioconcentrate in fish only to a minor degree.
- Executive summary:
The bioconcentration factor BCF was calculated using EPIWIN v3.20, BCFWIN v2.17. The estimation yielded a BCF of 0.4749. Based on the result, it can be assumed that acetophenone will bioconcentrate in fish only to a minor degree. The result was obtained from a generally accepted calculation method and therefore regarded as valid.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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