Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 231-977-3 | CAS number: 7783-06-4
Epidemiological data
Administrative data
- Endpoint:
- epidemiological data
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Secondary source
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Lung health in relation to hydrogen sulfide exposure in oil and gas workers in Alberta
- Author:
- Hessel PA; Herbert FA; Melenka LS; et al.
- Year:
- 1 997
- Bibliographic source:
- Canada. Am. J. Ind. Med., 31(5), 554-557
- Reference Type:
- secondary source
- Title:
- TOXICOLOGICAL REVIEW OF HYDROGEN SULFIDE (CAS No. 7783-06-4). In Support of Summary Information on the Integrated Risk Information System (IRIS)
- Author:
- U.S. Environmental Protection Agency
- Year:
- 2 003
- Bibliographic source:
- EPA/635/R-03/005. www.epa.gov/iris
Materials and methods
- Endpoint addressed:
- other: lung function
Test material
- Reference substance name:
- Hydrogen sulphide
- EC Number:
- 231-977-3
- EC Name:
- Hydrogen sulphide
- Cas Number:
- 7783-06-4
- Molecular formula:
- H2S
- IUPAC Name:
- hydrogen sulfide
Constituent 1
Results and discussion
Applicant's summary and conclusion
- Executive summary:
The pulmonary effects resulting from H2S exposure were assessed in 175 workers who extracted and processed oil and gas. The workers received a questionnaire concerning sour gas exposures that caused symptoms or loss of consciousness. Thirty-four percent of the respondents indicated that they had exposures serious enough to cause symptoms, and 8% of the workers stated they had experienced a loss of consciousness due to sour gas exposure. In workers that experienced symptoms, no decrease in spirometric values or excess symptoms were noted. While spirometric values were also not affected in workers that lost consciousness, the workers experienced shortness of breath during physical activity, wheezing with tightness in the chest, and wheezing attacks. The investigators stated that these symptoms are consistent with bronchial hyperresponsiveness. The data also demonstrate the refractiveness of the lung to the effects of H2S, with lung function parameters being unchanged despite unconsciousness from H2S
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
