Registration Dossier
Registration Dossier
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EC number: 200-824-2 | CAS number: 74-95-3
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Additional information
Dibromomethane was moderate and moderate to severely irritating to the skin and eye in rabbits. Redness, itching, and pain, well defined moderate-severe erythema and well define oedema were observed in a skin irritation assay. These effects were transient and reversible.
In the eye irritation assay, response to treatment included moderate pain, slight conjunctive and corneal injury of the rabbits eye. Very slight iritic. Healing was essentially complete in two days, The response of the eye contact washed treatment rabbits included: slight conjunctivae irritation. Healing was essentially complete in one day.
Justification for selection of skin irritation / corrosion endpoint:
Reliable study.
Justification for selection of eye irritation endpoint:
Reliable study.
Effects on skin irritation/corrosion: moderately irritating
Effects on eye irritation: moderately irritating
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
