Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 210-765-4 | CAS number: 623-03-0
Endpoint summary
Administrative data
Description of key information
For the photochemical oxidative degradation of 4-chlorobenzonitrile an atmospheric half-life of 66 days can be calculated (AOP v1.91).
The hydrolysis half-life of 4-chlorobenzonitrile at 37 °C at pH 7.7 is 170 days. Transformation products are 4-chlorobenzoic acid and 4-chlorobenzamide.
4-chlorobenzonitrile is not readily biodegradable in a test were the test substance was incubated with primary effluent of raw municipal sewage acclimated to non-chlorinated compounds at an initial concentration of 2mmol/L at 29 °C. The degradation of the test substance was followed by photometric measurements of anorganic chlorine that was released in connection with the decomposition of 4-chlorobenzonitrile. 2.1 - 4.2 % organic chlorine were released as inorganic chlorine after 2 days by sewage sludge acclimated to various nonchlorinated compounds.
In experiments investigating the degradation of 4-chlorobenzonitrile in anaerobic sediment systems under laboratory conditions, a degradation half-life of approximately 19 d could be determined.
Based on a vapour pressure of 0.03 hPa and a water solubility of 0.11 g/L a Henry constant of 3.7 Pa m³/mol can be calculated (HENRYWIN v3.10). This value indicates that 4-chlorobenzonitrile is moderately volatile from water.
From the calculated Koc of 159 (log Koc = 2.24) it can be concluded that 4-chlorobenzonitrile has only a low potential for adsorption to soil and sediments.
According to BUA Stoffbericht 265 adsorption to aerosols is not expected; adsorption of 4-chlorobenzonitrile to aerosol particles is less than 0.1 %.
Experimental data regarding the bioaccumulation potential of 4-chlorobenzonitrile are not available. QSAR estimated BCF values range between 10.6 and 29.7, indicating that 4-chlorobenzonitrile has only a low potential for bioaccumulation.
Distribution modeling using Mackay Level I (v.2.11, 1999) indicates that water (55.4 %) and air (43.4 %) are the main target compartments of 4-chlorobenzonitrile.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
