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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
other:
Remarks:
This study was performed with limited detail and was performed prior to establishment of OECD or EU guidelines. Considering the consistency of the results for all routes of exposure, it can be considered that DIDP has a low potential for acute toxicity.
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: The study is rated a "4" because it predates GLP and limited details are provided.

Data source

Reference
Reference Type:
publication
Title:
Studies on the toxicity of phthalates via ingestion
Author:
Krauskopf, LG
Year:
1973
Bibliographic source:
Environmental Health Perspectives, p 61-72

Materials and methods

GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
1,2-Benzenedicarboxylic acid, di-C9-11-branched alkyl esters, C10-rich
EC Number:
271-091-4
EC Name:
1,2-Benzenedicarboxylic acid, di-C9-11-branched alkyl esters, C10-rich
Cas Number:
68515-49-1
Molecular formula:
C28 H46 O4
IUPAC Name:
1,2-Benzenedicarboxylic acid, di-C9-11-branched alkyl esters, C10 rich
Constituent 2
Reference substance name:
1,2-benzenedicarboxylic acid, di-C9,C10 and C11 branched alkyl ester, C10 Rich
IUPAC Name:
1,2-benzenedicarboxylic acid, di-C9,C10 and C11 branched alkyl ester, C10 Rich

Test animals

Species:
other: rat and rabbit

Administration / exposure

Route of administration:
oral: unspecified
Doses:
single dose

Results and discussion

Effect levelsopen allclose all
Sex:
not specified
Dose descriptor:
LD50
Effect level:
29 100 mg/kg bw
Remarks on result:
other: rat
Sex:
not specified
Dose descriptor:
LD50
Effect level:
29 100 mg/kg bw
Remarks on result:
other: rabbit
Mortality:
non-lethal
Clinical signs:
other:

Applicant's summary and conclusion

Interpretation of results:
practically nontoxic
Remarks:
Migrated information Criteria used for interpretation of results: not specified
Conclusions:
The test substance is assumed to have a low order of acute toxicity by the oral route. The LD50 was reported to be 29,100 mg/kg in rats and in rabbits, a minimum lethal dose of 21,825-29,100 mg/kg has been calculated