Registration Dossier
Registration Dossier
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EC number: 915-617-9 | CAS number: -
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
An OECD TG 203 study in compliance with GLP criteria with Fathead minnow (Pimephales promelas) is available for the test substance. Fish (10/concentration) were exposed to nominal concentrations of 10, 18, 29, 48 and 80 mg/L under static renewal conditions (media renewed after 48 hours) for 96 hours. The test concentrations were analytically verified and determined as 8.21, 15.1, 24.3, 42.5 and 73 mg/L (82 - 91% of nominal concentrations). Test conditions were maintained constant throughout the test. The dissolved oxygen concentration has been at least 60% of the air saturation value throughout the test. At 15.1 mg/L test level, 80% mortality was observed. At higher concentrations, mortality was 100%. Sublethal effects were also noted and consisted of one or more of the following: loss of equilibrium, immobilisation, lethargy. Based on these findings, the 96-hour LC50 was determined to be 11.8 mg/L (95% C.L. is 10.2 to 13.6 mg/L).
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Dose descriptor:
- LC50
- Effect concentration:
- 11.8 mg/L
Additional information
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