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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

A GLP-compliant OECD 201 guideline study with the freshwater alga Selenastrum capricornutum is available for Lyral. Algae were exposed to nominal concentrations of 0 (control), 6.5, 13, 25, 50, and 100 mg/L under static conditions for 72 hours. Initial measured concentrations of Lyral were: control nat analysed, 5.95, 11.9, 22.9, 45.7, and 98.4 mg/L (91 to 98% of nominal). Measured concentrations for samples collected at the end of the definitive test were ND, 2.00, 4.17, 11.0, 32.5, and 74.4 mg/L (31 to 74% of nominal). Initial measured concentrations were used for all calculations.
Exposure of algae to Lyral for 72 hours resulted in a median effective concentration (EC50) of 25.4 mg/L when calculated using the average specific growth rate, 13.7 mg/L when calculated using the number of cells/mL, and 13.8 mg/L when calculated using the area under the growth curve. The 72 hour no observed effect concentration (NOEC) is 5.95 mg/L Lyral when determined using the number of cells/mL, the average specific growth rate, and the area under the growth curve.

Key value for chemical safety assessment

EC50 for freshwater algae:
25.4 mg/L
EC10 or NOEC for freshwater algae:
5.95 mg/L

Additional information