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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Eye irritation

Currently viewing:

Administrative data

Endpoint:
eye irritation
Remarks:
no data
Type of information:
not specified
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Secondary citation. In the OECD SIDS on 2-Naphthol (2002) a similar reliability was assigned.

Data source

Reference
Reference Type:
secondary source
Title:
Industrial Bio-Test Laboratories, Inc., Data Sheets
Author:
Industrial Bio-Test Laboratories
Year:
1973
Bibliographic source:
As cited in: The Registry of Toxic Effects of Chemical Substances (RTECS).

Materials and methods

Principles of method if other than guideline:
no data

Test material

Constituent 1
Chemical structure
Reference substance name:
2-naphthol
EC Number:
205-182-7
EC Name:
2-naphthol
Cas Number:
135-19-3
Molecular formula:
C10H8O
IUPAC Name:
2-naphthol

Test animals / tissue source

Species:
rabbit
Strain:
not specified

Test system

Vehicle:
not specified
Controls:
not specified
Amount / concentration applied:
100 mg
Duration of treatment / exposure:
no data
Observation period (in vivo):
no data
Number of animals or in vitro replicates:
no data

Results and discussion

Applicant's summary and conclusion

Interpretation of results:
moderately irritating
Remarks:
Migrated information
Conclusions:
2-naphthol was reported in the RTECs database to be moderately irritating to eyes on rabbits for an amount of 100 mg.