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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
not specified
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Secondary citation. In the OECD SIDS on 2-Naphthol (2002) a similar reliability was assigned.

Data source

Reference
Reference Type:
secondary source
Title:
No information
Author:
Rakhmanin
Year:
1965
Bibliographic source:
Gig. Sanit. 30(9), 22-28; As cited in: The Registry of Toxic Effects of Chemical Substances (RTECS).

Materials and methods

Principles of method if other than guideline:
no data
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
2-naphthol
EC Number:
205-182-7
EC Name:
2-naphthol
Cas Number:
135-19-3
Molecular formula:
C10H8O
IUPAC Name:
2-naphthol

Test animals

Species:
rat
Strain:
not specified
Sex:
male

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified
Doses:
No data
No. of animals per sex per dose:
No data
Control animals:
not specified

Results and discussion

Effect levels
Sex:
male
Dose descriptor:
LD50
Effect level:
1 960 mg/kg bw
Based on:
not specified

Applicant's summary and conclusion

Conclusions:
A LD50 of 1960 mg/kg bw on male rat was cited in The Registry of Toxic Effects of Chemical Substances (RTECS) database.