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EC number: 219-283-9 | CAS number: 2402-79-1
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 16 January 1991 to 19 February 1992
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP study conducted in compliance with agreed protocols, with no or minor deviations from standard test guidelines.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 992
- Report date:
- 1992
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- column elution method
- Remarks:
- A shake flask method was also used.
Test material
- Reference substance name:
- 2,3,5,6-tetrachloropyridine
- EC Number:
- 219-283-9
- EC Name:
- 2,3,5,6-tetrachloropyridine
- Cas Number:
- 2402-79-1
- Molecular formula:
- C5HCl4N
- IUPAC Name:
- 2,3,5,6-tetrachloropyridine
- Details on test material:
- Lot number WP900914-748 of purity = 98.6%
Constituent 1
Results and discussion
Water solubilityopen allclose all
- Water solubility:
- 29.84 mg/L
- Temp.:
- 23 °C
- pH:
- 6.82
- Water solubility:
- 22.6 mg/L
- Temp.:
- 20 °C
- pH:
- 6.82
Any other information on results incl. tables
Water solubility determined by the shake flask method
Sample* |
Concentration (mg/l) |
Mean +/- S.D. (mg/l) |
Centrifuged** No. 1 No.2 |
31.23 29.20 |
30.22 +/- 1.44 |
Filtered |
29.84 |
29.84 |
*the pH of the saturated solution of the substance was 6.82
**duplicate samples
Water solubility determined by the column elution method
Fraction collected* |
Flow rate (ml/min) |
Average concentration** +/- S.D. (mg/l) |
I |
0.5 |
23.4 +/- 0.8 |
II |
0.5 |
20.9 +/- 1.4 |
III |
0.5 |
21.0 +/- 1.2 |
VI |
1.0 |
24.6 +/- 2.0 |
V |
1.0 |
23.1 +/- 1.0 |
|
|
Mean: 22.6 +/- 1.6 |
*each fraction represents 5 replicates
**average of 5 replicates
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The water solubility of the substance has been determined to be 29.84 mg/l at 23 deg C by the shake flask method and 22.6 mg/l at 20 deg C by the column elution method. - Executive summary:
The water solubility of the substance has been determined to be 29.84 mg/l at 23 deg C by the shake flask method and 22.6 mg/l at 20 deg C by the column elution method. Both methods were conducted in accordance with OECD Guideline number 105.
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