Registration Dossier
Registration Dossier
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EC number: 219-283-9 | CAS number: 2402-79-1
Particle size distribution (Granulometry)
Administrative data
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 23 June 2009 to 10 July 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP study conducted in compliance with agreed protocols, with no or minor deviations from standard test guidelines.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 009
- Report date:
- 2009
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of distribution:
- volumetric distribution
Test material
- Reference substance name:
- 2,3,5,6-tetrachloropyridine
- EC Number:
- 219-283-9
- EC Name:
- 2,3,5,6-tetrachloropyridine
- Cas Number:
- 2402-79-1
- Molecular formula:
- C5HCl4N
- IUPAC Name:
- 2,3,5,6-tetrachloropyridine
- Details on test material:
- Lot number XF09160201 of purity = 99.4%
Constituent 1
Results and discussion
Particle size
- Percentile:
- D50
- Remarks on result:
- other: Migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.
Particle size distribution at different passages
- No.:
- #1
- Size:
- < 100 µm
- Distribution:
- 6.09 %
Any other information on results incl. tables
Sieve aperture size (µm) |
100 |
Mass of test material transferred to sieve (g) |
11.5 |
Mass of test material passed through sieve (g) |
0.7 |
Test material less than sieve aperture size (%) |
6.09 |
Applicant's summary and conclusion
- Conclusions:
- The proportion of test material having an inhalable particle size less than 100 µm was determined to be 6.09 % and considered to be essentially non-inhalable.
- Executive summary:
The particle size distribution of the substance has been assessed using a sieve method in compliance with that given in "Particle Size Distribution, Fibre Length and Diameter Distribution", June 1996 European Commission technical guidance document, which satisfies the requirements of OECD Guideline 110. The proportion of test material having an inhalable particle size less than 100µm was determined to be 6.09 % and the substance is therefore considered to be essentially non-inhalable.
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