Registration Dossier

Diss Factsheets

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
0.32 µg/L
Assessment factor:
10
Extrapolation method:
assessment factor
PNEC freshwater (intermittent releases):
0.13 µg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
32 ng/L
Assessment factor:
100
Extrapolation method:
assessment factor
PNEC marine water (intermittent releases):
13 ng/L

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
10 mg/L
Assessment factor:
10
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
0.155 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
15.5 µg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
30.8 µg/kg soil dw
Extrapolation method:
equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
PNEC oral
PNEC value:
0.33 mg/kg food
Assessment factor:
300

Additional information

Conclusion on classification

The environmental classification of 2,5-bis(1,1-dimethylpropyl)-1,4-diol is currently not harmonized according to the CLP Regulation (EC) 1272/2008.

 

Short-term toxicity tests resulted in L(E)C50 values below 1 mg/L for both fish (96-h LC50 = 0.013 mg/L) and daphnids (48-h EC50 = 0.91 mg/L). Long-term studies gave the following results;NOEC for freshwater fish: 3.2µg/L; NOEC for freshwater invertebrates: 11µg/L. Based on these results and due to the fact that 2,5-bis(1,1-dimethylpropyl)-1,4-diol is not readily biodegradable, this substance should be classified in Acute Category 1 and Chronic Category 1 for the aquatic environment according to Annex 1 (section 4.1.2.6) of the CLP Regulation.

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